Effects of imatinib mesylate on spontaneous electrical and mechanical activity in smooth muscle of the guineapig stomach

H Hashitani, M Hayase, H Suzuki - British journal of …, 2008 - Wiley Online Library
activity were investigated by measuring changes in the membrane potential and tension
recorded from smooth muscles of the guinea-pig stomach. Its effects on spontaneous changes …

Effects of imatinib mesylate on the spontaneous activity generated by the guineapig prostate

M Lam, A Dey, RJ Lang, B Exintaris - BJU international, 2013 - Wiley Online Library
… wave activity arising from the guinea-pig stomach 13, leading the authors to suggest that
imatinib mesylate also has non-specific effects… and mechanical activity of smooth muscle organs …

Imatinib blocks spontaneous mechanical activities in the adult mouse small intestine: possible inhibition of c-Kit signaling

N Shimojima, T Nakaki, Y Morikawa, K Hoshino… - Pharmacology, 2005 - karger.com
muscles were investigated in ring preparations of the gut. … nonspecific effects of imatinib on
smooth muscle contraction, … TK: Propagation of pacemaker activity in the guinea-pig antrum. J …

Effects of imatinib mesylate (Glivec®) as ac‐kit tyrosine kinase inhibitor in the guineapig urinary bladder

Y Kubota, SM Biers, K Kohri… - … and Urodynamics: Official …, 2006 - Wiley Online Library
… measured in guinea-pig detrusor smooth muscle using conventional … In the gut they occur in
dense electrically interconnected … spontaneous electrical, calcium and mechanical activity in …

The effect of imatinib mesylate on the contractility of isolated rabbit myometrial strips

G Hutchings, J Deprest, B Nilius, T Roskams… - Gynecologic and …, 2006 - karger.com
… contractions in smooth muscle derived from the gut of mice [9] … vitro effect of imatinib on the
spontaneous contractile activity … inhibitor Glivec on isolated guinea-pig detrusor preparations. …

The functional effects of ac‐kit tyrosine inhibitor on guineapig and human detrusor

SM Biers, JM Reynard, T Doore, AF Brading - BJU international, 2006 - Wiley Online Library
Imatinib mesylate (10 −6 M) inhibited evoked smooth muscle contraction and spontaneous
activity … A small lower midline abdominal incision was made in the abdomen, the bladder was …

Imatinib relaxes the pulmonary venous bed of guinea pigs

NA Maihöfer, S Suleiman, D Dreymüller, PW Manley… - Respiratory …, 2017 - Springer
… on the relaxant effects of imatinib in the pulmonary venous bed. We selected GPs, as the
access to human lung tissue is limited and the pulmonary smooth muscle pharmacology of GPs …

Effect of prolonged c-kit receptor inhibition by imatinib mesylate on the uterine contractility of pregnant rabbits

G Hutchings, T Gevaert, J Deprest, B Nilius… - Gynecologic and …, 2008 - karger.com
… In the smooth muscle of the gastrointestinal tract, interstitial … of these cells in electrical signaling
in the gut and suggest that … inhibitor Glivec on isolated guinea-pig detrusor preparations. …

Effects of imatinib mesylate in interstitial cells of Cajal from murine small intestine

BJ Kim, H Chae, YK Kwon, S Choi, JY Jun… - Biological and …, 2010 - jstage.jst.go.jp
… contractile activity in various phasic smooth muscles, … gall bladder14) and guinea pig
stomach.However, none of … , imatinib predominantly reduces the amplitude of spontaneous

Complex effects of imatinib on spontaneous and oxytocin-induced contractions in human non-pregnant myometrium

S Cretoiu, A Simionescu, L Caravia… - Acta Physiologica …, 2011 - akjournals.com
… Hashitani H, Hayase M, Suzuki H: Effects of imatinib mesylate on spontaneous electrical
and mechanical activity in smooth muscle of the guinea-pig stomach. Br. J. …